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2025 Week 5 NFL Fantasy Injury Preview

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2025 Week 5 NFL Fantasy Injury Preview

Follow Dr. Edwin Porras on his fantasy football account here and see what his day job is in the Denver area

The following notable players are OUT in Week 5:

Lamar Jackson - Hamstring

Projected Return: Week 6-8

Terry McLaurin - Quad

Projected Return: Week 6-7

Chuba Hubbard - Calf

Projected Return: Week 7-8

Bucky Irving - Ankle/Shoulder

Projected Return: Week 7-8

Trey Benson - Meiscus

Projected Return: Week 9-10

J.J. McCarthy - High Ankle

Projected Return: Week 6-7

CeeDee Lamb - High Ankle

Projected Return: Week 6-7

Mike Evans: Hamstring

Projected Return: Week 6-8

Brandon Aiyuk - ACL

Projected Return: Week 6-8

Joe Burrow - Toe

Projected Return: 2026

Tyrone Tracy - Shoulder

Projected Return: Week 6-8

James Conner - Ankle

Projected Return: 2026

Najee Harris - Achilles

Projected Return: 2026

Tyreek Hill - Knee Dislocation

Projected Return: 2026

Malik Nabers - ACL

Projected Return: 2026

Brock Bowers - Knee

The Week 1 injury was likely a bone bruise which with rest, can take 2-4 weeks to really feel better. Considering he’s playing on it, the lack of practice is (probably) just rest. Expect him to go with added reinjury risk.

Jayden Daniels - Knee

Coming off the vague “knee sprain” Daniels carries a 14% reinjury risk and on average QBs see a 10% dip in production but importantly they see nearly a 40% dip in rushing yards. Given the Chargers are a team that is specifically vulnerable to the QB run, Daniels is likely safe to start in 12 person and 2 QB leagues but isn’t a good cash game play.

Jaxson Dart - Hamstring

This hamstring is something for DFS players to watch out for as a rusher. Reinjurying this is on the radar if he keeps running as much as he has been (about 15% reinjury rate).

Edwin completed his Doctorate of Physical Therapy education in 2020. His expertise is in all thing’s orthopedics, injury recovery, and he has a special interest in human performance. Edwin’s vision is to push injury advice past simple video analysis and into the realm of applying data from the medical literature to help fantasy players make informed start-sit decisions.