You’ve used Fantasy Points — notably our 2025 League-Winners, Targets, and Values — to build a competitive roster before you get to the end of your draft. The last pick or two of your fantasy drafts are never irrelevant. You can win leagues with those selections. Hence “Mr. Relevant.”
When you get to the conclusion of your draft, that’s the time to consider swinging for the fences. “Boring” players, those capable of providing you 8 to 10 PPR fantasy points in a pinch, are constantly available on the Waiver Wire throughout the season. These are not the kinds of players we want to recommend in this article. Consider those players “singles,” to borrow a baseball term.
We’re trying to hit the ball out of the ballpark. This article will have far more strikeouts than home runs, but that’s the point — we’re trying to predict who the hot Waiver Wire pickups will be before they become hot Waiver Wire pickups.
Speaking of home runs, last year’s Mr. Relevant article was another great one. We highlighted league-altering players like Bucky Irving, Tyrone Tracy, Jordan Mason, Bo Nix, Sam Darnold, Darnell Mooney, Josh Downs, and Zach Ertz. Let’s get to the players who we’re targeting 150 or more picks into fantasy drafts, who we believe feature that kind of upside.
This article will be constantly updated throughout the preseason. ADP in this article is based on our ADP tool’s PPR setting, which pulls from NFFC drafts over the last 14 days.
Quarterbacks
Trevor Lawrence (Jax, ADP 166 QB21, PROJ QB15)
Entering his fifth season, it’s time for Lawrence to fish or cut bait. Jacksonville fired Doug Pederson and hired Liam Coen to try his hand at getting the most out of the 2021 first overall pick. Coen guided Baker Mayfield to career-bests in yards (4500), TDs (41), YPA (7.9), completion percentage (71.4%), passer rating (106.8), and FPG (22.6) in his first season as NFL playcaller. His next mission is to fully unlock the talented Lawrence. T-Law owns a 3.4% TD rate, a 6.8 YPA average, and an 85.0 passer rating through his first four seasons. Lawrence averaged a respectable 16.9 FPG in his nine full contests last season, which would’ve placed him as the QB15 over the full season. He missed two games for a non-throwing shoulder injury before suffering a season-ending concussion on an illegal hit from Azeez Al-Shaair in Week 13.
The Jaguars are fully committed to his success after signing him to a five-year contract extension last season. Lawrence has one of the most promising young WRs to throw to in Brian Thomas, and they added to his weaponry by moving up to select two-way threat Travis Hunter second overall. Lawrence isn’t prolific enough of a runner to elevate into the elite tier at the position this season, but he averages 3.9 attempts and 18.1 rushing YPG with 14 rushing TDs to start his career. He has the physical tools, the receivers, and now the coaching to finish as a top-10 fantasy QB for the first time in his fifth season if he can finally raise his game to the next level.
Bryce Young (Car, ADP 197 QB24, PROJ QB25)
Young and the Panthers got off to a rough start in Dave Canales’ first season as head coach, but the offense trended up in the back half of 2024. Young threw for TDs in 10 straight games once he was inserted back into the starting lineup in Week 8, tossing 15 total TDs with a 4.7% TD rate during that span. He previously threw for TDs in 8 of his first 18 NFL starts, tossing just 11 TDs with a 1.9% TD rate to begin his career. Young ranked first in hero throw rate (7.8%), fourth in scrambles (30), and eighth in deep throw rate (14.1%) in the final 10 weeks, throwing to the likes of Adam Thielen, Xavier Legette, and Jalen Coker.
Young has a chance to maintain or improve his 4.7% TD rate from the end of last season after the Panthers selected Tetairoa McMillan eighth overall. He scored 18 TDs in his final 25 games at Arizona, and he could become Canales’ new Mike Evans near the end zone at 6’4”, 219 pounds. Young finished the season strong as the QB1 (36.4) in Week 18 and as the QB2 (27.1) in Week 16. He has more rushing upside than expected after running for 6 scores last season, and he’s averaging 2.9 attempts and 17.6 rushing YPG in his first 28 starts. His rushing production took off in the final eight games last season, averaging 3.8 attempts and 26.0 rushing YPG with 5 rushing TDs. Young has an outside shot to finish as a top-12 QB if he continues to scramble like he did at the end of last season, and if McMillan can significantly elevate this passing attack as a rookie.
